The Balanced ECC83S is located in V2 which is physically farthest from the instrument input jacks.

Combo amps are very hard on tubes because of vibrations which can cause tube rattle with any brand of tube. If your amp is the combo version and you play by yourself in a quiet environment or record with your amp you may want to consider using the EuroDamper tube damper rings for the two power tubes. These are available in the "Related Products” tab as a set of two large dampers and will greatly decrease tube rattle